Florida favored to win Saturday’s NHL matchup [10/18/2025]


The Buffalo Sabres will square off with the Florida Panthers in NHL action at KeyBank Center on Saturday, starting at 1:00PM ET.

Based on updated simulation results, Dimers’ proven NHL model predicts the Panthers as the most likely winner of today’s game.

For expanded analysis of Saturday’s matchup, including best bets and player prop picks, visit our interactive Panthers vs. Sabres predictions page.

Panthers vs. Sabres prediction: Who will win, cover the puck line?

Using powerful machine learning and data, we have simulated the result of Saturday’s NHL matchup between the Panthers and Sabres 10,000 times as part of our NHL predictions coverage.

Our leading predictive model gives the Panthers a 57% chance of beating the Sabres.

According to our model, the Sabres (+1.5) have a 64% chance of covering the puck line, while the over/under total of 6 goals has a 51% chance of going over.

 

Panthers vs. Sabres odds

We have sourced the best NHL odds in America for this game, which are listed here:

Bet Type Panthers Sabres
Puck Line -1.5 (+170) +1.5 (-200)
Moneyline -142 +125
Total o6 (-110) u6 (-110)

All odds are correct at the time of publication and are subject to change.

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Panthers vs. Sabres picks and best bets

Our model’s biggest edge in today’s Panthers vs. Sabres matchup is on the puck line.

Our expert predictions, aligned with the current odds, reveal the best NHL picks and NHL best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Panthers vs. Sabres player props

Who will score an anytime goal in Panthers vs. Sabres?

According to our model, Florida’s Sam Reinhart is most likely to score the first goal in Panthers vs. Sabres.

Our projections give Reinhart a 9.3% chance of scoring the first goal at KeyBank Center, while the Panthers star is a 43.5% chance of netting an anytime goal.

First goal scorer predictions

Florida Panthers

Player First Goal Probability
Sam Reinhart 9.3%
Brad Marchand 6.4%
Sam Bennett 5.6%

Buffalo Sabres

Player First Goal Probability
Tage Thompson 7.7%
Alex Tuch 5.9%
Jason Zucker 4.6%

Anytime goal scorer predictions

Florida Panthers

Player Anytime Goal Probability
Sam Reinhart 43.5%
Brad Marchand 32.2%
Sam Bennett 31.2%

Buffalo Sabres

Player Anytime Goal Probability
Tage Thompson 40.2%
Alex Tuch 30.8%
Jason Zucker 25.2%

Panthers vs. Sabres game-day updates and essential details

Saturday’s game between the Sabres and Panthers at KeyBank Center is scheduled to begin at 1:00PM ET.

Dimers’ in-depth preview of Saturday’s Panthers vs. Sabres matchup includes our prediction, picks and the latest betting odds.

Before making any Panthers vs. Sabres picks, be sure to check out the latest NHL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Panthers, with a 57% win probability, will likely beat the Sabres on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Panthers vs. Sabres insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on NHL

Keep up with the latest NHL betting news and parlay picks throughout the season. Plus, our Stanley Cup odds provide the latest predictions for the Stanley Cup title.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.



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