Wednesday’s slate in the NHL includes a matchup between the Buffalo Sabres and the Detroit Red Wings.
Before you make your wager on FanDuel Sportsbook, we’ve got you covered, in terms of the most important information regarding today’s NHL betting odds.
Sabres vs Red Wings Game Info
- Buffalo Sabres (2-4) vs. Detroit Red Wings (5-1)
- Date: Wednesday, October 22, 2025
- Time: 7:30 p.m. ET
- Venue: KeyBank Center — Buffalo, New York
- Coverage: TNT
Sabres vs Red Wings Odds
All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.
Sabres vs Red Wings Prediction & Pick
All NHL win probability predictions and picks are according to numberFire.
- Prediction: Sabres win (52.9%)
Sabres vs Red Wings Puck Line
- The Sabres are 1.5-goal favorites against the Red Wings. The Sabres are +210 to cover the spread, and the Red Wings are -265.
Sabres vs Red Wings Over/Under
- A total of 6.5 goals has been set for the Sabres-Red Wings matchup on Oct. 22, with the over available at +112 and the under at -138.
Sabres vs Red Wings Moneyline
- Looking at the moneyline for Sabres-Red Wings, Buffalo is the favorite at -113, and Detroit is -108 playing on the road.